Takahiko Tokuda Selected Research

Genetic Anticipation

9/2007	Severe amyloid deposition in mammary glands of familial amyloid polyneuropathy patients.
6/2004	Deposition of transthyretin amyloid is not accelerated by the same amyloid in vivo.

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Takahiko Tokuda Research Topics

Disease

24	Parkinson Disease (Parkinson's Disease) 01/2021 - 04/2003
21	Alzheimer Disease (Alzheimer's Disease) 01/2021 - 08/2003
11	Dementia (Dementias) 01/2019 - 08/2003
9	Amyloidosis 01/2009 - 03/2003
8	Disease Progression 01/2022 - 01/2010
7	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2022 - 01/2009
6	Neurodegenerative Diseases (Neurodegenerative Disease) 03/2022 - 11/2012
6	Parkinsonian Disorders (Parkinsonism) 10/2020 - 01/2010
4	Cognitive Dysfunction 01/2017 - 03/2009
4	Familial Amyloid Neuropathies (Familial Amyloid Polyneuropathy) 09/2007 - 02/2002
3	Multiple System Atrophy 01/2020 - 01/2016
3	Down Syndrome (Down's Syndrome) 01/2019 - 08/2004
3	Polyneuropathies (Polyneuropathy) 03/2006 - 03/2002
2	Meningitis 03/2020 - 02/2009
2	Hydrocephalus (Hydrocephaly) 03/2020 - 01/2018
2	Sarcoma (Soft Tissue Sarcoma) 01/2018 - 08/2014
2	Muscular Diseases (Myopathy) 01/2017 - 12/2010
2	Amyloid Plaque 12/2015 - 12/2002
2	Synucleinopathies 01/2014 - 01/2009
2	Corticobasal Degeneration 01/2013 - 01/2013
2	Tauopathies 01/2013 - 01/2013
2	Carpal Tunnel Syndrome 01/2009 - 03/2003
2	Cardiomyopathies (Cardiomyopathy) 01/2009 - 03/2003
2	Genetic Anticipation 09/2007 - 06/2004
2	Rheumatoid Arthritis 03/2005 - 02/2004
1	Central Nervous System Infections (Central Nervous System Infection) 01/2021
1	Spinal Muscular Atrophy (Progressive Muscular Atrophy) 03/2020
1	Hemorrhage 03/2020
1	Prodromal Symptoms 01/2020
1	Traumatic Brain Injuries (Traumatic Brain Injury) 01/2019
1	Inclusion Body Myositis 01/2019
1	Renal Insufficiency (Renal Failure) 01/2019
1	Liposarcoma 01/2018
1	Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar) 01/2018
1	Myeloid Leukemia (Leukemia, Myelocytic) 01/2018
1	Nervous System Diseases (Neurological Disorders) 01/2017
1	Hemolytic Anemia 01/2017
1	Seizures (Absence Seizure) 01/2017
1	Hemolysis 01/2015
1	Exanthema (Rash) 09/2014
1	Creutzfeldt-Jakob Syndrome (Creutzfeldt-Jakob Disease) 06/2014
1	Dermatomyositis (Dermatopolymyositis) 05/2014
1	Atrophy 01/2014
1	Movement Disorders (Movement Disorder) 01/2013
1	Memory Disorders (Memory Loss) 06/2012
1	Neuromyelitis Optica (Devic's Disease) 04/2011
1	Pathologic Constriction (Stenosis) 02/2010

Drug/Important Bio-Agent (IBA)

29	Biomarkers (Surrogate Marker)IBA 03/2022 - 07/2009
15	Amyloid (Amyloid Fibrils)IBA 01/2021 - 06/2004
15	Proteins (Proteins, Gene)FDA Link 01/2021 - 03/2003
14	SynucleinsIBA 01/2021 - 01/2012
8	alpha-SynucleinIBA 10/2017 - 10/2006
8	Prealbumin (Transthyretin)IBA 01/2009 - 03/2002
5	DNA-Binding Proteins (DNA Binding Protein)IBA 01/2021 - 01/2009
4	Pharmaceutical PreparationsIBA 06/2019 - 10/2003
3	3-Iodobenzylguanidine (Iobenguane)IBA 12/2019 - 08/2003
3	Intravenous Immunoglobulins (IVIG)FDA Link 01/2017 - 03/2006
3	Amyloid beta-PeptidesIBA 08/2010 - 12/2002
2	Neuroprotective AgentsIBA 01/2020 - 01/2018
2	Caffeine (No Doz)FDA LinkGeneric 01/2020 - 01/2018
2	Indicators and Reagents (Reagents)IBA 01/2019 - 02/2010
2	Peptides (Polypeptides)IBA 01/2018 - 06/2012
2	Levodopa (L Dopa)FDA LinkGeneric 01/2017 - 04/2003
2	AntibodiesIBA 01/2017 - 01/2015
2	EnzymesIBA 10/2016 - 04/2004
2	tau Proteins (tau Protein)IBA 01/2013 - 01/2013
2	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2010 - 03/2005
2	AcidsIBA 07/2009 - 03/2005
2	Prednisolone (Predate)FDA LinkGeneric 01/2006 - 03/2005
1	N,N-dimethylarginine (asymmetric dimethylarginine)IBA 01/2022
1	Phosphoglycerate Kinase (Kinase, Phosphoglycerate)IBA 10/2020
1	nusinersenIBA 03/2020
1	Leucine (L-Leucine)FDA Link 01/2020
1	Phosphotransferases (Kinase)IBA 01/2020
1	Protein AggregatesIBA 01/2019
1	Iodine-123IBA 11/2018
1	NucleophosminIBA 01/2018
1	Theophylline (Theon)FDA LinkGeneric 01/2018
1	proadrenomedullinIBA 01/2017
1	Adenosine Triphosphate (ATP)IBA 01/2017
1	Serum AlbuminIBA 12/2016
1	GlobulinsIBA 12/2016
1	Tocopherols (Tocopherol)IBA 10/2016
1	ImmunosorbentsIBA 10/2016
1	Serine (L-Serine)FDA Link 10/2016
1	Selegiline (E250)FDA LinkGeneric 10/2016
1	Transferrin (beta 2 Transferrin)IBA 08/2016
1	Monoclonal AntibodiesIBA 01/2016
1	coenzyme Q10 (CoQ10)IBA 01/2016
1	SolutionsIBA 09/2014
1	RNA-Binding Proteins (RNA-Binding Protein)IBA 08/2014
1	formycin diphosphate (FDP)IBA 05/2014
1	Pemetrexed (MTA)FDA Link 01/2014
1	Aquaporins (Water Channels)IBA 04/2011
1	Bortezomib (Velcade)FDA Link 12/2010

Therapy/Procedure

5	Therapeutics 01/2018 - 02/2004
3	Liver Transplantation 04/2004 - 02/2002
1	Renal Dialysis (Hemodialysis) 01/2019
1	Immunotherapy 01/2017
1	Intravenous Infusions 09/2014